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Hendrick is attributed with the formalization of organizational design and management (ODAM) in ergonomics [Hendrick, H.W., Kleiner, B.M., 2001. Macroergonomics: An Introduction to Work System Design. Human Factors and Ergonomics Society, Santa Monica, CA.]. Specifically, the method called “Macroergonomic Analysis of Structure” or MAS provides a framework and analysis of these factors and provides the context for an analysis of organizational design and management process through the MacroErgonomic Analysis and Design method (MEAD). Together, MAS and MEAD represent the formalization of staple methods in macroergonomics and can be used to organize existing tools and methods such as those that exist in systems safety and help to differentiate macroergonomics from other approaches. This article illustrates such an integrative role for macroergonomics with respect to systems safety using …