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Retroperitoneal lipoma has been considered as the rarest case experienced in the clinical scenario. The reported cases in the literature have been very scarce in count. We report a case of a 57-year-old female, with a history of pain and diffuse swelling over abdomen. Radiological imaging such as abdominal ultrasonography and computed tomography (CT) scans of the abdomen showed a large mass located in the retroperitoneal space. Laparotomy showed a large encapsulated tumor measuring 40 cm× 30 cm× 10 cm and weighing 8 kg. The histological study revealed a benign neoplasm of fatty cells. The patient had a good postoperative performance status. Since the occurrence of lipoma in the retroperitoneum is considered rare, fat containing lesions in the region of the retroperitoneum and around can never be taken as simple diffusion or pedunculated lipoma. Pelvic lipomatosis is the overgrowth of histologically normal fat in the extra abdominal compartments of the pelvis along the perirectal and perivesical spaces. Along with the radiological appearances, the clinical features and demographic details are highly helpful in the zeroing the diagnosis and management protocol of the case. Lipoma should be considered in the differential diagnosis of a solid tumor in the retroperitoneal space and the treatment of retroperitoneal lipoma is eminently surgical.