作者
Mila Donker, Marieke E Straver, Jelle Wesseling, Claudette E Loo, Margaret Schot, Caroline A Drukker, Harm van Tinteren, Gabe S Sonke, J Emiel, Marie-Jeanne TFD Vrancken Peeters
发表日期
2015/2/1
期刊
Annals of surgery
卷号
261
期号
2
页码范围
378-382
出版商
LWW
简介
Objective:
The MARI procedure [marking the axillary lymph node with radioactive iodine (125 I) seeds] is a new minimal invasive method to assess the pathological response of nodal metastases after neoadjuvant systemic treatment (NST) in patients with breast cancer. This method allows axilla-conserving surgery in patients responding well to NST.
Methods:
Prior to NST, proven tumor-positive axillary lymph nodes were marked with a 125 I seed. This marked lymph node is the so-called MARI-node. After NST, the MARI node was selectively removed using a γ-detection probe. A complementary axillary lymph node dissection was performed in all patients to assess whether pathological response in the MARI node was indicative for the pathological response in the additional lymph nodes.
Results:
A tumor-positive axillary lymph node was marked with a 125 I seed in 100 patients. The MARI node was successfully …
学术搜索中的文章
M Donker, ME Straver, J Wesseling, CE Loo, M Schot… - Annals of surgery, 2015