作者
Diane M Papazian, Leslie C Timpe, Yuh Nung Jan, Lily Y Jan
发表日期
1991/1/24
期刊
Nature
卷号
349
期号
6307
页码范围
305-310
出版商
Nature Publishing Group UK
简介
Voltage-dependent potassium, sodium and calcium ion channels may share a common mechanism of activation, in which the conserved S4 sequence acts as the primary voltage sensor. Site-directed mutagenesis of the S4 sequence of the Shaker potassium channel and electrophysiological analysis suggest that voltage-dependent activation involves the S4 sequence but is not solely due to electrostatic interactions.
引用总数
学术搜索中的文章
DM Papazian, LC Timpe, YN Jan, LY Jan - Nature, 1991