作者
Jorge T Dias, María Moros, Pablo del Pino González de la Higuera, Sara Rivera-Fernández, Valeria Grazú
发表日期
2013
出版商
Wiley-VCH
简介
The magnetism of magnetic nanoparticles (MNPs)[1] has found many useful applications in nanomedicine. Among them, heating using MNPs shows great potential and is currently the focus of intensive research.[2] This process relies on the capability of the magnetic dipole of MNPs to couple to an AMF and subsequently, dissipating the absorbed energy by releasing heat.[3] Heating using MNPs has proven to be very useful for magnetic fluid hyperthermia promoting cell death [4] or controlled drug release.[5] In fact, strong thermal confinement using collective heating released by MNPs has already been demonstrated to induce localized heating, enabling the activation of ion channels and neurons.[6] Measurements of absolute temperature of NPs have been reported using a luminescent molecular thermometer based on rare earth chelating agents.[7] Rinaldi and Polo-Corrales showed that iron oxide nanoparticles could thermally induce changes in fluorescence of a thermoresponsive/fluorescent polymer coating the NPs.[8] However their work is limited to the cause and consequence of surpassing one single value of temperature. Assessment of local temperature increments in comparison with the global temperature of the surrounding medium, and temperature gradients with respect to increasing distances away from the MNP surface, has proven so far to be a challenging task. Recently, a remarkable study by Riedinger et al.[9] has shown a very accurate measurement of the surface temperature profile of NPs, based on the thermal decomposition of a thermo-sensitive molecule. They were able to determine the absolute temperature at …
引用总数
201320142015201620172018201920202021202220232024110181012122112154104
学术搜索中的文章