作者
Christoph Gasche, Jurgen Scholmerich, Jorn Brynskov, Geert D'Haens, Stephen B Hanauer, E Jan Irvine, Derek P Jewell, Daniel Rachmilewitz, David B Sachar, William J Sandborn, Lloyd R Sutherland
发表日期
2000/2
期刊
Inflammatory bowel diseases
卷号
6
期号
1
页码范围
8-15
出版商
Lippincott Williams & Wilkins, Inc.
简介
Crohn's disease is a heterogeneous entity. Previous attempts of classification have been based primarily on anatomic location and behavior of disease. However, no uniform definition of patient subgroups has yet achieved broad acceptance. The aim of this international Working Party was to develop a simple classification of Crohn's disease based on objective variables. Eight outcome‐related variables relevant to Crohn's disease were identified and stepwise evaluated in 413 consecutive cases, a database survey, and by clinical considerations. Allocation of variables was conducted with well‐defined Crohn's disease populations from Europe and North America. Cross‐table analyses were performed by chi‐square testing. Three variables were finally elected: Age at Diagnosis [below 40 years (A1), equal to or above 40 years (A2)], Location [terminal ileum (L1), colon (L2), ileocolon (L3). upper gastro‐intestinal …
引用总数
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