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Sperm DNA damage is the major cause of defective sperm function. Poor social habits take a toll not only on reproductive health of parents but the resultant offspring too. Adopting a holistic integrated approach like mindfulness based stress reduction (MBSR), a yoga based intervention have gained significant impetus in recent years. This study aimed to analyze how mere a simple lifestyle change can bring about balance in seminal oxidative stress parameters and related consequences in next generations.

Out of 126 fathers of children with non-familial sporadic heritable Retinoblastoma (NFSHRb), 102 were randomized into 2 groups i.e. MBSR group and Non-MBSR group. Parameters of seminal oxidative stress (OS) and oxidative DNA damage (ODD) were measured at baseline (0 day) and after 4 weeks in both groups.

There was significant decrease (p < 0.0001) in mean reactive …