作者
Bart G Pijls, Shahab Jolani, Anique Atherley, Raissa T Derckx, Janna IR Dijkstra, Gregor HL Franssen, Stevie Hendriks, Anke Richters, Annemarie Venemans-Jellema, Saurabh Zalpuri, Maurice P Zeegers
发表日期
2021/1/1
期刊
BMJ open
卷号
11
期号
1
页码范围
e044640
出版商
British Medical Journal Publishing Group
简介
Objective
We aimed to describe the associations of age and sex with the risk of COVID-19 in different severity stages ranging from infection to death.
Design
Systematic review and meta-analysis.
Data sources
PubMed and Embase through 4 May 2020.
Study selection
We considered cohort and case–control studies that evaluated differences in age and sex on the risk of COVID-19 infection, disease severity, intensive care unit (ICU) admission and death.
Data extraction and synthesis
We screened and included studies using standardised electronic data extraction forms and we pooled data from published studies and data acquired by contacting authors using random effects meta-analysis. We assessed the risk of bias using the Newcastle-Ottawa Scale.
Results
We screened 11.550 titles and included 59 studies comprising 36.470 patients in the analyses. The methodological quality of the included papers was high (8.2 …
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BG Pijls, S Jolani, A Atherley, RT Derckx, JIR Dijkstra… - BMJ open, 2021