作者
Kallol Ray Chaudhuri, Pablo Martinez‐Martin, Richard G Brown, Kapil Sethi, Fabrizio Stocchi, Per Odin, William Ondo, Kazuo Abe, Graeme MacPhee, Doug MacMahon, Paolo Barone, Martin Rabey, Alison Forbes, Kieran Breen, Susanne Tluk, Yogini Naidu, Warren Olanow, Adrian J Williams, Sue Thomas, David Rye, Yoshio Tsuboi, Annette Hand, Anthony HV Schapira
发表日期
2007/10/15
期刊
Movement disorders
卷号
22
期号
13
页码范围
1901-1911
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Non‐motor symptoms (NMS) in Parkinson's disease (PD) are common, significantly reduce quality of life and at present there is no validated clinical tool to assess the progress or potential response to treatment of NMS. A new 30‐item scale for the assessment of NMS in PD (NMSS) was developed. NMSS contains nine dimensions: cardiovascular, sleep/fatigue, mood/cognition, perceptual problems, attention/memory, gastrointestinal, urinary, sexual function, and miscellany. The metric attributes of this instrument were analyzed. Data from 242 patients mean age 67.2 ± 11 years, duration of disease 6.4 ± 6 years, and 57.3% male across all stages of PD were collected from the centers in Europe, USA, and Japan. The mean NMSS score was 56.5 ± 40.7, (range: 0–243) and only one declared no NMS. The scale provided 99.2% complete data for the analysis with the total score being free of floor and ceiling effect …
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