作者
L Keoki Williams, Manel Pladevall, Hugo Xi, Edward L Peterson, Christine Joseph, Jennifer Elston Lafata, Dennis R Ownby, Christine C Johnson
发表日期
2004/12/1
期刊
Journal of Allergy and Clinical Immunology
卷号
114
期号
6
页码范围
1288-1293
出版商
Mosby
简介
BACKGROUND
Regular use of inhaled corticosteroids (ICSs) can improve asthma symptoms and prevent exacerbations. However, overall adherence is poor among patients with asthma.
OBJECTIVE
To estimate the proportion of poor asthma-related outcomes attributable to ICS nonadherence.
METHODS
We retrospectively identified 405 adults age 18 to 50 years who had asthma and were members of a large health maintenance organization in southeast Michigan between January 1, 1999, and December 31, 2001. Adherence indices were calculated by using medical records and pharmacy claims. The main outcomes were the number of asthma-related outpatient visits, emergency department visits, and hospitalizations, as well as the frequency of oral steroid use.
RESULTS
Overall adherence to ICS was approximately 50%. Adherence to ICS was significantly and negatively correlated with the number of …
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Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma
LK Williams, M Pladevall, H Xi, EL Peterson, C Joseph… - Journal of Allergy and Clinical Immunology, 2004