查看文章

The effect of the ethanol extracts of Curcuma longa Linn (yellow turmeric) and Curcuma zedoaria Rosc (white turmeric) on cardiac oxidative stress in rats exposed to manganese was evaluated in this study.

We divided 60 Wistar rats into 12 groups (n=5) with some administered different concentrations of yellow or white turmeric extract. The animals except the control groups were exposed to manganese on days 1,3, and 7. All the animals were sacrificed on the 8^th day and the hearts were harvested for biochemical assays. Ferric-reducing antioxidant power (FRAP) and the levels of cardiac superoxide dismutase, reduced glutathione, nitric oxide, and lipid peroxidation in rats were determined. Additionally, in silico studies were performed to further compare the cardioprotective potential of the two species of turmeric.

The results showed that rats treated with manganese alone had decreased …