作者
Claire Philippat, Dorothy Nakiwala, Antonia M Calafat, Jérémie Botton, Maria De Agostini, Barbara Heude, Rémy Slama, EDEN Mother–Child Study Group
发表日期
2017/9/15
期刊
Environmental health perspectives
卷号
125
期号
9
页码范围
097014
简介
Background
Sex-specific associations have been reported between phthalates, bisphenol A (BPA), and child behavior. No data on large study populations are available for other phenols with possible endocrine-disrupting properties.
Objectives
We aimed to study associations between prenatal exposure to phthalates and several phenols on behavior among male infants.
Methods
We quantified 11 phthalate metabolites and nine phenols (four parabens, benzophenone-3, BPA, two dichlorophenols, triclosan) in spot urine samples collected during pregnancy among EDEN cohort mothers who delivered a boy. Mothers completed the Strength and Difficulties Questionnaire (SDQ) when their children were 3.1 () and 5.6 () y old.
Results
BPA was positively associated with the relationship problems subscale at 3 y [incidence rate ratio (IRR): 1.11; 95% confidence interval (CI): 1.03, 1.20] and the …
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C Philippat, D Nakiwala, AM Calafat, J Botton… - Environmental health perspectives, 2017