作者
Eleni Papadopoulou, Jérémie Botton, Anne-Lise Brantsæter, Margaretha Haugen, Jan Alexander, Helle Margrete Meltzer, Jonas Bacelis, Anders Elfvin, Bo Jacobsson, Verena Sengpiel
发表日期
2018/3/1
期刊
BMJ open
卷号
8
期号
3
页码范围
e018895
出版商
British Medical Journal Publishing Group
简介
Objectives
To study the association between maternal caffeine intake during pregnancy and the child’s weight gain and overweight risk up to 8 years.
Design
Prospective nationwide pregnancy cohort.
Setting
The Norwegian Mother and Child Cohort Study.
Participants
A total of 50 943 mothers recruited from 2002 to 2008 and their children, after singleton pregnancies, with information about average caffeine intake assessed at mid-pregnancy.
Outcome measure
Child’s body size information at 11 age points from 6 weeks to 8 years. We defined excess growth in infancy as a WHO weight gain z-score of >0.67 from birth to age 1 year, and overweight according to the International Obesity Task Force. We used a growth model to assess individual growth trajectories.
Results
Compared with pregnant women with low caffeine intake (<50 mg/day, 46%), women with average (50–199 mg/day, 44%), high (≥200–299 mg …
学术搜索中的文章
E Papadopoulou, J Botton, AL Brantsæter, M Haugen… - BMJ open, 2018