作者
Arefeh Basiri, Arash Heidari, Melina Farshbaf Nadi, Mohammad Taha Pahlevan Fallahy, Sasan Salehi Nezamabadi, Mohammadreza Sedighi, Amene Saghazadeh, Nima Rezaei
发表日期
2021/1
来源
Reviews in medical virology
卷号
31
期号
1
页码范围
1-11
简介
There is a long way to go before the coronavirus disease 2019 (Covid‐19) outbreak comes under control. qRT‐PCR is currently used for the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of Covid‐19, but it is expensive, time‐consuming, and not as sensitive as it should be. Finding a rapid, easy‐to‐use, and cheap diagnostic method is necessary to help control the current outbreak. Microfluidic systems provide a platform for many diagnostic tests, including RT‐PCR, RT‐LAMP, nested‐PCR, nucleic acid hybridization, ELISA, fluorescence‐Based Assays, rolling circle amplification, aptamers, sample preparation multiplexer (SPM), Porous Silicon Nanowire Forest, silica sol‐gel coating/bonding, and CRISPR. They promise faster, cheaper, and easy‐to‐use methods with higher sensitivity, so microfluidic devices have a high potential to be an alternative method for the …
引用总数
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A Basiri, A Heidari, MF Nadi, MTP Fallahy… - Reviews in medical virology, 2021