作者
Seyed Aria Nejadghaderi, Arash Heidari, Narges Shakerian, Amene Saghazadeh, Nima Rezaei
发表日期
2020
来源
Acta Bio Medica: Atenei Parmensis
卷号
91
期号
3
页码范围
e2020018
出版商
Mattioli 1885
简介
SARS-CoV-2 has shown its potential to cause severe manifestations among individuals with underlying cardiovascular disease (CVD). The patients infected with SARS-CoV-2 with pre-existing CVD are more likely to relapse. There are several reasons, including the prolonged hospitalization time as a consequence of their more severe illness and aberrant expression of angiotensin-converting enzyme 2 (ACE2)–the cell surface receptor of SARS-COV2 that is present on cardiac cells–and using drugs such as ACE inhibitors and angiotensin receptor blockers (ARBs) that alter the expression of ACE2. Besides, SARS-CoV-2 shares structural similarities with SARS-CoV-1, and that patients recovered from SARS-CoV1 have shown an increased risk of developing inflammatory, metabolic, and cardiac diseases. It makes some concerns that people who recovered from SARS-CoV2 are also liable to develop these chronic …
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SA Nejadghaderi, A Heidari, N Shakerian… - Acta Bio Medica: Atenei Parmensis, 2020