作者
Riccardo Valdagni, Vittorio Vavassori, Tiziana Rancati, Gianni Fellin, Micaela Baccolini, Carla Bianchi, Emanuela Cagna, Pietro Gabriele, Floranna Mauro, Loris Menegotti, Angelo Filippo Monti, Michele Stasi, Claudio Fiorino
发表日期
2012/5/1
期刊
Radiotherapy and Oncology
卷号
103
期号
2
页码范围
252-255
出版商
Elsevier
简介
PURPOSE
To evaluate and discuss the role of specific types of abdominal surgery (SURG) before radical radiation therapy as a risk factor for late rectal toxicity in prostate cancer patients.
METHODS
Results concerning questionnaire-based scored late bleeding and faecal incontinence in 718 patients with a complete follow-up of 36months were analysed, focusing on the impact of specific pre-radiotherapy abdominal/pelvic surgery procedures. Patients were accrued in the prospective study AIROPROS 0102. Different types of surgery (rectum-sigma resection, kidney resection, cholecystectomy or appendectomy) were considered as covariates together with a number of different parameters previously found to be predictive of late toxicity and including clinical as well as dosimetric parameters. Univariate (UVA) and multivariate (MVA) logistic analyses were carried out.
RESULTS
In total 69/718 patients were …
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R Valdagni, V Vavassori, T Rancati, G Fellin… - Radiotherapy and Oncology, 2012