作者
Gianni Fellin, Claudio Fiorino, Tiziana Rancati, Vittorio Vavassori, Micaela Baccolini, Carla Bianchi, Emanuela Cagna, Pietro Gabriele, Floranna Mauro, Loris Menegotti, Angelo Filippo Monti, Michele Stasi, Riccardo Valdagni
发表日期
2009/11/1
期刊
Radiotherapy and Oncology
卷号
93
期号
2
页码范围
197-202
出版商
Elsevier
简介
PURPOSE
Assessing the predictors of late rectal toxicity after high-dose conformal radiotherapy for prostate cancer.
METHODS
One thousand one hundred thirty-two patients entered a prospective observational multicentric study; late rectal toxicity was evaluated by a self-reported questionnaire. Results concerning bleeding and faecal incontinence of 718/1132 patients with a complete follow-up at 36months were analysed. The correlation between a number of clinical–dosimetric parameters and moderate/severe toxicity was investigated by univariate and multivariate logistic analyses.
RESULTS
Fifty-two (7.2%) and 57/718 (7.9%) patients were scored as moderate/severe bleeders and faecal incontinence, respectively; 19/57 incontinent patients showed persistent incontinence at 36months. Bleeding was mainly correlated with V75Gy while severe bleeding was mainly correlated with the previous abdominal/pelvic …
学术搜索中的文章
G Fellin, C Fiorino, T Rancati, V Vavassori, M Baccolini… - Radiotherapy and Oncology, 2009