作者
Marco Ripa, Laura Galli, Andrea Poli, Chiara Oltolini, Vincenzo Spagnuolo, Andrea Mastrangelo, Camilla Muccini, Giacomo Monti, Giacomo De Luca, Giovanni Landoni, Lorenzo Dagna, Massimo Clementi, Patrizia Rovere Querini, Fabio Ciceri, Moreno Tresoldi, Adriano Lazzarin, Alberto Zangrillo, Paolo Scarpellini, Antonella Castagna, Andrea Andolina, Martina Baiardo Redaelli, Giorgia Bigai, Alba Bigoloni, Giorgia Borio, Simona Bossolasco, Elena Bruzzesi, Maria Grazia Calabrò, Stefania Calvisi, Corrado Campochiaro, Diana Canetti, Valentina Canti, Jacopo Castellani, Barbara Castiglioni, Giulio Cavalli, Ludovica Cavallo, Massimo Cernuschi, Matteo Chiurlo, Marta Cilla, Elena Cinel, Paola Cinque, Caterina Conte, Valentina Da Prat, Anna Danise, Rebecca De Lorenzo, Antonio Dell’Acqua, Raffaele Dell’Acqua, Emanuel Della Torre, Liviana Della Torre, Gaetano Di Terlizzi, Iulia Dumea, Federica Farolfi, Marica Ferrante, Claudia Frangi, Luca Fumagalli, Gabriele Gallina, Bruno Germinario, Nicola Gianotti, Monica Guffanti, Hamid Hasson, Francesca Lalla, Marco Lanzillotta, Raffaele Li Voti, Emanuela Messina, Chiara Molinari, Elena Moizo, Marco Montagna, Giulia Morsica, Silvia Nozza, Maria Pascali, Alessandro Patrizi, Marina Pieri, Antonella Poloniato, Dario Prestifilippo, Giuseppe Ramirez, Martina Ranzenigo, Jacopo Sapienza, Federico Seghi, Giuseppe Tambussi, Chiara Tassan Din, Stefano Turi, Caterina Uberti-Foppa, Concetta Vinci
发表日期
2021/3/1
期刊
Clinical Microbiology and Infection
卷号
27
期号
3
页码范围
451-457
出版商
Elsevier
简介
Objectives
The aim of our study was to describe the incidence and predictive factors of secondary infections in patients with coronavirus disease 2019 (COVID-19).
Methods
This was a cohort study of patients hospitalized with COVID-19 at IRCCS San Raffaele Hospital between 25th February and 6th April 2020 (NCT04318366). We considered secondary bloodstream infections (BSIs) or possible lower respiratory tract infections (pLRTIs) occurring 48 hours after hospital admission until death or discharge. We calculated multivariable Fine–Gray models to assess factors associated with risk of secondary infections.
Results
Among 731 patients, a secondary infection was diagnosed in 68 patients (9.3%); 58/731 patients (7.9%) had at least one BSI and 22/731 patients (3.0%) at least one pLRTI. The overall 28-day cumulative incidence was 16.4% (95%CI 12.4–21.0%). Most of the BSIs were due to Gram-positive …
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M Ripa, L Galli, A Poli, C Oltolini, V Spagnuolo… - Clinical Microbiology and Infection, 2021