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In an age where technology is evolving at a sometimes incomprehensibly rapid pace, the liver community must adjust and learn to embrace breakthroughs with an open mind in order to benefit from potentially transformative influences on our science and practice. The Journal of Hepatology has responded to novel developments in artificial intelligence (AI) by recruiting experts in the field to serve on the Editorial Board. Publications introducing novel AI technology are no longer uncommon in our journal and are among the most highly debated and possibly practice-changing papers across a broad range of scientific disciplines, united by their focus on liver disease. As AI is rapidly evolving, this expert paper will focus on educating our readership on large language models and their possible impact on our research practice and clinical outlook, outlining both challenges and opportunities in the field.

“To improve is to …