作者
Shahin Homaeigohar, Aldo R Boccaccini
发表日期
2020/4/15
来源
Acta biomaterialia
卷号
107
页码范围
25-49
出版商
Elsevier
简介
Globally, chronic wounds impose a notable burden to patients and healthcare systems. Such skin wounds are readily subjected to bacteria that provoke inflammation and hence challenge the healing process. Furthermore, bacteria induce infection impeding re-epithelialization and collagen synthesis. With an estimated global market of $20.4 billion by 2021, appropriate wound dressing materials e.g. those composed of biopolymers originating from nature, are capable of alleviating the infection incidence and of accelerating the healing process. Particularly, biopolymeric nanofibrous dressings are biocompatible and mostly biodegradable and biomimic the extracellular matrix structure. Such nanofibrous dressings provide a high surface area and the ability to deliver antibiotics and antibacterial agents locally into the wound milieu to control infection. In this regard, with the dangerous evolution of antibiotic resistant …
引用总数
学术搜索中的文章
S Homaeigohar, AR Boccaccini - Available at SSRN 3490423, 2019