作者
Sheng-Yang Huang, Chia-Man Chou, Tsung-Han Chen, Pei-Chuen Chiou, Vincent KS Hsiao, Congo Tak-Shing Ching, Tai-Ping Sun
发表日期
2014/4/8
期刊
Journal of the Electrochemical Society
卷号
161
期号
5
页码范围
B102
出版商
IOP Publishing
简介
This paper successfully demonstrates that a sensing device, with a microfluidic channel, integrated with interdigitated microelectrode (IDμE), is able to detect different glucose concentrations without immobilizing enzymes onto the surface of microelectrodes. Phosphate buffered saline (PBS) solution (10X) was used as a sensing medium and the measurement frequency determines the device sensitivity. Higher measurement frequency enhances sensitivity. A model of an equivalent circuit is proposed and a theoretical simulation and calculation are fitted with the experimental data. The principle of measurement is based on changes in the dielectric constant of the analyte dissolved in the buffer solution at different concentrations. Thus, an increased sensitivity is obtained at a higher measurement frequency (4 MHz). The sensing device demonstrated here has potential for application to disposable polymer lab-on-a …
学术搜索中的文章
SY Huang, CM Chou, TH Chen, PC Chiou, VKS Hsiao… - Journal of the Electrochemical Society, 2014