作者
C-K Peng, Sergej V Buldyrev, Ary L Goldberger, Shlomo Havlin, Francesco Sciortino, Michael Simons, H Eugene Stanley
发表日期
1992/3/12
期刊
Nature
卷号
356
期号
6365
页码范围
168-170
出版商
Nature Publishing Group UK
简介
DNA SEQUENCES have been analysed using models, such as an it-step Markov chain, that incorporate the possibility of short-range nucleotide correlations1. We propose here a method for studying the stochastic properties of nucleotide sequences by constructing a 1:1 map of the nucleotide sequence onto a walk, which we term a 'DNA walk'. We then use the mapping to provide a quantitative measure of the correlation between nucleotides over long distances along the DNA chain. Thus we uncover in the nucleotide sequence a remarkably long-range power law correlation that implies a new scale-invariant property of DNA. We find such long-range correlations in intron-containing genes and in nontranscribed regulatory DNA sequences, but not in complementary DNA sequences or intron-less genes.
引用总数
学术搜索中的文章
CK Peng, SV Buldyrev, AL Goldberger, S Havlin… - Nature, 1992