作者
Rolando Pajon, Nicole A Doria-Rose, Xiaoying Shen, Stephen D Schmidt, Sijy O’Dell, Charlene McDanal, Wenhong Feng, Jin Tong, Amanda Eaton, Maha Maglinao, Haili Tang, Kelly E Manning, Venkata-Viswanadh Edara, Lilin Lai, Madison Ellis, Kathryn M Moore, Katharine Floyd, Stephanie L Foster, Christine M Posavad, Robert L Atmar, Kirsten E Lyke, Tongqing Zhou, Lingshu Wang, Yi Zhang, Martin R Gaudinski, Walker P Black, Ingelise Gordon, Mercy Guech, Julie E Ledgerwood, John N Misasi, Alicia Widge, Nancy J Sullivan, Paul C Roberts, John H Beigel, Bette Korber, Lindsey R Baden, Hana El Sahly, Spyros Chalkias, Honghong Zhou, Jing Feng, Bethany Girard, Rituparna Das, Anne Aunins, Darin K Edwards, Mehul S Suthar, John R Mascola, David C Montefiori
发表日期
2022/3/17
期刊
New England Journal of Medicine
卷号
386
期号
11
页码范围
1088-1091
出版商
Massachusetts Medical Society
简介
Omicron Neutralization and mRNA-1273 Boosters
Neutralization of the omicron variant was assessed in serum samples obtained from persons who had received an mRNA-1273 booster. After the standard two-dose vaccine regimen, these titers were approximately 35 times lower than those against the D614G variant. However, boosters increased omicron neutralization by a factor of 20 — to levels that correlate with clinical resistance to infection.
学术搜索中的文章
R Pajon, NA Doria-Rose, X Shen, SD Schmidt, S O'Dell… - New England Journal of Medicine, 2022