作者
Giovanni Luigi De Maria, Roberto Scarsini, Mayooran Shanmuganathan, Rafail A Kotronias, Dimitrios Terentes-Printzios, Alessandra Borlotti, Jeremy P Langrish, Andrew J Lucking, Robin P Choudhury, Rajesh Kharbanda, Vanessa M Ferreira, Oxford Acute Myocardial Infarction (OXAMI) Study Investigators, Keith M Channon, Hector M Garcia-Garcia, Adrian P Banning
发表日期
2020/8
期刊
The international journal of cardiovascular imaging
卷号
36
页码范围
1395-1406
出版商
Springer Netherlands
简介
Immediate assessment of coronary microcirculation during treatment of ST elevation myocardial infarction (STEMI) may facilitate patient stratification for targeted treatment algorithms. Use of pressure-wire to measure the index of microcirculatory resistance (IMR) is possible but has inevitable practical restrictions. We aimed to develop and validate angiography-derived index of microcirculatory resistance (IMRangio) as a novel and pressure-wire-free index to facilitate assessment of the coronary microcirculation. 45 STEMI patients treated with primary percutaneous coronary intervention (pPCI) were enrolled. Immediately before stenting and at completion of pPCI, IMR was measured within the infarct related artery (IRA). At the same time points, 2 angiographic views were acquired during hyperaemia to measure quantitative flow ratio (QFR) from which IMRangio was derived. In a subset of 15 patients both IMR and …
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GL De Maria, R Scarsini, M Shanmuganathan… - The international journal of cardiovascular imaging, 2020