作者
Michael S McCloskey, Antonia S New, Larry J Siever, Marianne Goodman, Harold W Koenigsberg, Janine D Flory, Emil F Coccaro
发表日期
2009/8/1
期刊
Journal of psychiatric research
卷号
43
期号
12
页码范围
1036-1048
出版商
Pergamon
简介
Borderline personality disorder (BPD) is marked by aggression and impulsive, often self-destructive behavior. Despite the severe risks associated with BPD, relatively little is known about the disorder’s etiology. Identification of genetic correlates (endophenotypes) of BPD would improve the prospects of targeted interventions for more homogeneous subsets of borderline patients characterized by specific genetic vulnerabilities. The current study evaluated behavioral measures of aggression and impulsivity as potential endophenotypes for BPD. Subjects with BPD (N=127), a non cluster B personality disorder (OPD N=122), or healthy volunteers (HV N=112) completed self report and behavioral measures of aggression, motor impulsivity and cognitive impulsivity. Results showed that BPD subjects demonstrated more aggression and motor impulsivity than HV (but not OPD) subjects on behavioral tasks. In contrast …
引用总数
20092010201120122013201420152016201720182019202020212022202320241711920151482513225141188
学术搜索中的文章