作者
Casey R Guillot, Jennifer R Fanning, Joshua S Bullock, Michael S McCloskey, Mitchell E Berman
发表日期
2010/10
期刊
Experimental and clinical psychopharmacology
卷号
18
期号
5
页码范围
409
出版商
American Psychological Association
简介
Alcohol has been shown to affect performance on tasks associated with executive functioning. However, studies in this area have generally been limited to a single dose or gender or have used small sample sizes. The purpose of this study was to provide a more nuanced and systematic examination of alcohol's effects on commonly used tests of executive functioning at multiple dosages in both men and women. Research volunteers (91 women and 94 men) were randomly assigned to one of four drink conditions (alcohol doses associated with target blood alcohol concentrations of. 000%,. 050%,. 075%, and. 100%). Participants then completed three tasks comprising two domains of executive functioning: two set shifting tasks, the Trail Making Test and a computerized version of the Wisconsin Card Sorting Task, and a response inhibition task, the GoStop Impulsivity Paradigm. Impaired performance on set shifting …
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CR Guillot, JR Fanning, JS Bullock, MS McCloskey… - Experimental and clinical psychopharmacology, 2010