作者
Vivek Dhar Dwivedi, Aditya Arya, Pardeep Yadav, Rajesh Kumar, Vinod Kumar, Gajendra PS Raghava
发表日期
2021/5
期刊
Briefings in Bioinformatics
卷号
22
期号
3
页码范围
bbaa098
出版商
Oxford University Press
简介
Dengue virus (DENV) researchers often face challenges with the highly time-consuming process of collecting and curating information on known inhibitors during the standard drug discovery process. To this end, however, required collective information is not yet available on a single platform. Hence, we have developed the DenvInD database for experimentally validated DENV inhibitors against its known targets presently hosted at https://webs.iiitd.edu.in/raghava/denvind/. This database provides comprehensive information, i.e. PubChem IDs, SMILES, IC50, EC50, CC50, and wherever available Ki values of the 484 compounds in vitro validated as inhibitors against respective drug targets of DENV. Also, the DenvInD database has been linked to the user-friendly web-based interface and accessibility features, such as simple search, advanced search and data browsing. All the required data curation was …
引用总数
20212022202320242563
学术搜索中的文章
VD Dwivedi, A Arya, P Yadav, R Kumar, V Kumar… - Briefings in Bioinformatics, 2021