作者
Akhlaque Uddin, Timothy A Fairbairn, Ibrahim K Djoukhader, Mark Igra, Ananth Kidambi, Manish Motwani, Bernhard Herzog, David P Ripley, Tarique Al Musa, Anthony JP Goddard, Daniel J Blackman, Sven Plein, John P Greenwood
发表日期
2015/3
期刊
Circulation: Cardiovascular Interventions
卷号
8
期号
3
页码范围
e001913
出版商
Lippincott Williams & Wilkins
简介
Background
Incidence of cerebral microinfarcts is higher after transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR). It is unknown whether these lesions persist and what direct impact they have on health-related quality of life. The objective was to identify predictors of cerebral microinfarction and measure their effect on health-related quality of life during 6 months after TAVI when compared with SAVR.
Methods and Results
Cerebral MRI was conducted at baseline, post procedure, and 6 months using diffusion-weighted imaging. Health-related quality of life was measured at baseline, 30 days, and 6 months with short form-12 health outcomes and EuroQol 5 dimensions questionnaires. One hundred eleven patients (TAVI, n=71; SAVR, n=40) were studied. The incidence (54 [77%] versus 17 [43%]; P=0.001) and number (3.4±4.9 versus 1.2±1.8; P=0.001) of new …
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A Uddin, TA Fairbairn, IK Djoukhader, M Igra… - Circulation: Cardiovascular Interventions, 2015