作者
Mohd Ahmar Rauf, Mohammad Oves, Fawad Ur Rehman, Abdur Rauf Khan, Nazim Husain
发表日期
2019/8/1
期刊
Biomedicine & Pharmacotherapy
卷号
116
页码范围
108983
出版商
Elsevier Masson
简介
The zinc oxide nanomaterials (ZnO-NMs), owing to their broad biomedical applications have lately attracted the incredible interest in the development of therapeutic agents against microbial infections. In this contribution, we have biosynthesized ZnO-NMs with a size of ˜ 40 nm from the Bougainvillea flower extracts. The FTIR and SEM-EDX mapping analysis confirmed the size, shape and biogenic origin of ZnO-NPs. Furthermore, the purified ZnO-NMs were applied for antibacterial studies against susceptible and resistant bacterial strains and to elucidate the possible mechanism of their activity. The XTT assay and confocal imaging confirmed the ZnO-NMs materials anti-biofilm activities against medically important pathogens, i.e., S. aureus and E. coli. Moreover, the absence of cytotoxicity against healthy kidney cells (HEK-293) and erythrocytes confirmed their biocompatible nature. Furthermore, the biosynthesized …
学术搜索中的文章
MA Rauf, M Oves, FU Rehman, AR Khan, N Husain - Biomedicine & Pharmacotherapy, 2019