作者
Matthew K Burrage, Mayooran Shanmuganathan, Qiang Zhang, Evan Hann, Iulia A Popescu, Rajkumar Soundarajan, Kelvin Chow, Stefan Neubauer, Vanessa M Ferreira, Stefan K Piechnik
发表日期
2021/6/30
期刊
Scientific Reports
卷号
11
期号
1
页码范围
13568
出版商
Nature Publishing Group UK
简介
Stress and rest T1-mapping may assess for myocardial ischemia and extracellular volume (ECV). However, the stress T1 response is method-dependent, and underestimation may lead to misdiagnosis. Further, ECV quantification may be affected by time, as well as the number and dosage of gadolinium (Gd) contrast administered. We compared two commonly available T1-mapping approaches in their stress T1 response and ECV measurement stability. Healthy subjects (n = 10, 50% female, 35 ± 8 years) underwent regadenoson stress CMR (1.5 T) on two separate days. Prototype ShMOLLI 5(1)1(1)1 sequence was used to acquire consecutive mid-ventricular T1-maps at rest, stress and post-Gd contrast to track the T1 time evolution. For comparison, standard MOLLI sequences were used: MOLLI 5(3)3 Low (256 matrix) & High (192 matrix) Heart Rate (HR) to acquire rest and stress T1-maps, and MOLLI 4(1)3(1 …
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MK Burrage, M Shanmuganathan, Q Zhang, E Hann… - Scientific Reports, 2021