作者
Mayooran Shanmuganathan, Ambra Masi, Matthew K Burrage, Rafail A Kotronias, Alessandra Borlotti, Roberto Scarsini, Abhirup Banerjee, Dimitrios Terentes-Printzios, Qiang Zhang, Evan Hann, Elizabeth Tunnicliffe, Andrew Lucking, Jeremy Langrish, Rajesh Kharbanda, Giovanni Luigi De Maria, Adrian P Banning, Robin P Choudhury, Keith M Channon, Stefan K Piechnik, Vanessa M Ferreira, OxAMI Study Investigators
发表日期
2023/1/1
期刊
Cardiovascular Imaging
卷号
16
期号
1
页码范围
46-59
出版商
American College of Cardiology Foundation
简介
Background
Acute ST-segment elevation myocardial infarction (STEMI) has effects on the myocardium beyond the immediate infarcted territory. However, pathophysiologic changes in the noninfarcted myocardium and their prognostic implications remain unclear.
Objectives
The purpose of this study was to evaluate the long-term prognostic value of acute changes in both infarcted and noninfarcted myocardium post-STEMI.
Methods
Patients with acute STEMI undergoing primary percutaneous coronary intervention underwent evaluation with blood biomarkers and cardiac magnetic resonance (CMR) at 2 days and 6 months, with long-term follow-up for major adverse cardiac events (MACE). A comprehensive CMR protocol included cine, T2-weighted, T2∗, T1-mapping, and late gadolinium enhancement (LGE) imaging. Areas without LGE were defined as noninfarcted myocardium. MACE was a composite of …
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