作者
Elizabeth W Thompson, Srikant Kamesh Iyer, Michael P Solomon, Zhaohuan Li, Qiang Zhang, Stefan Piechnik, Konrad Werys, Sophia Swago, Brianna F Moon, Zachary B Rodgers, Anya Hall, Rishabh Kumar, Nosheen Reza, Jessica Kim, Alisha Jamil, Benoit Desjardins, Harold Litt, Anjali Owens, Walter RT Witschey, Yuchi Han
发表日期
2021/12
期刊
Journal of Cardiovascular Magnetic Resonance
卷号
23
页码范围
1-9
出版商
BioMed Central
简介
Background
Hypertrophic cardiomyopathy (HCM) is characterized by increased left ventricular wall thickness, cardiomyocyte hypertrophy, and fibrosis. Adverse cardiac risk characterization has been performed using late gadolinium enhancement (LGE), native T1, and extracellular volume (ECV). Relaxation time constants are affected by background field inhomogeneity. T1ρ utilizes a spin-lock pulse to decrease the effect of unwanted relaxation. The objective of this study was to study T1ρ as compared to T1, ECV, and LGE in HCM patients.
Methods
HCM patients were recruited as part of the Novel Markers of Prognosis in Hypertrophic Cardiomyopathy study, and healthy controls were matched for comparison. In addition to cardiac functional imaging, subjects underwent T1 and T1ρ cardiovascular magnetic resonance imaging at short-axis positions at 1 …
学术搜索中的文章
EW Thompson, S Kamesh Iyer, MP Solomon, Z Li… - Journal of Cardiovascular Magnetic Resonance, 2021