作者
Muhammad S Qudus, Sheikh Arslan Sehgal, Jawad Ahmed, Momin Khan, Shahina Mumtaz, Muhammad Arshad, Sami Siraj
发表日期
2019/6/1
期刊
Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders)
卷号
19
期号
4
页码范围
443-448
出版商
Bentham Science Publishers
简介
Introduction
Pseudomonas aeruginosa is one of the major pathogens associated with the acute tissue damage in patients having Diabetic Foot Ulcer (DFU). The treatment of such infections can be an uphill battle due to the serious resistance to all the mainstay antibiotics, owing to overzealous production of Extended-Spectrum Beta-Lactamases (ESBLs). Pakistan also has a high prevalence of diabetes and complications related to it, however genetic disposition of the pathogens remains underinvestigated.
Aim
The main objective of the study was to determine the frequency of ESBLs in Multi-drug resistant P. aeruginosa from diabetic foot patients.
Methods
The duration of the present study was one year and 100 patients having DFU were enrolled. All the pus samples were subjected to the bacterial culture, gram staining, catalase test, oxidase test and antimicrobial susceptibility pattern to various antibiotics for the …
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MS Qudus, SA Sehgal, J Ahmed, M Khan, S Mumtaz… - Endocrine, Metabolic & Immune Disorders-Drug …, 2019