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The aim of this study was to analyze clinical and microbiological characters in subjects and implants affected and not affected by peri‐implantitis. Additionally, same features were analyzed also intra‐individually, comparing healthy and diseased implants within the same subject.

A total of 534 patients who received at least 1 implant and coming to routine check‐up or spontaneous visits at the University of Valencia were recruited. Clinical parameters including Bleeding on probing (BoP), Probing pocket depth (PPD), and Pi were screened. Samples for microbiological analysis were obtained from three locations: peri‐implant sulci (PIS), inner parts of the implant connections (I), and gingival sulci of neighboring teeth (GS). Quantitative real‐time PCR was performed for total counts of 10 microorganisms.

A total of 534 patients with 1507 dental implants were analyzed. The …