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Little is known about how the intensity of aerobic training influences appetite-regulating hormones in obese adolescents. Our goal was to assess the effect of low and high intensity aerobic trainings on food intake and appetite-regulating hormones in obese adolescents. Forty three obese adolescents (age: 13–18y, BMI: 34.48 ± 3.94 kg/m ² ) were randomized into high intensity training (HIT; n = 20) or low intensity training (LIT; n = 23) groups for 12 weeks. All participants also received the same nutritional, psychological and clinical counseling. Pre- and postintervention energy intake (EI) and circulating levels of insulin, leptin, peptide YY _3–36 (PYY _3–36 ) and ghrelin were measured. Adolescents in the HIT showed a reduction in total EI and an increase in PYY _3–36 ( p < .05). Aerobic exercise training performed at …