作者
Matthew J Gurka, Sherita H Golden, Solomon K Musani, Mario Sims, Abhishek Vishnu, Yi Guo, Michelle Cardel, Thomas A Pearson, Mark D DeBoer
发表日期
2017/7
期刊
Diabetologia
卷号
60
期号
7
页码范围
1261-1270
出版商
Springer Berlin Heidelberg
简介
Aims/hypothesis
The study aimed to assess for an association between the degree of severity of the metabolic syndrome and risk of type 2 diabetes beyond that conferred by the individual components of the metabolic syndrome.
Methods
We assessed HRs for an Adult Treatment Panel III (ATP-III) metabolic syndrome score (ATP-III MetS) and a sex- and race-specific continuous metabolic syndrome severity z score related to incident diabetes over a median of 7.8 years of follow-up among participants of two observational cohorts, the Atherosclerosis Risk in Communities study (n = 10,957) and the Jackson Heart Study (n = 2137).
Results
The ATP-III MetS had an HR for incident diabetes of 4.36 (95% CI 3.83, 4.97), which was attenuated in models that included the individual metabolic syndrome components. By contrast …
引用总数
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