作者
Adi Nosrati, Jacqueline G Berliner, Shilpa Goel, Joseph McGuire, Vera Morhenn, Juliana R de Souza, Yıldıray Yeniay, Rasnik Singh, Kristina Lee, Mio Nakamura, Rachel R Wu, Ann Griffin, Barbara Grimes, Eleni Linos, Mary Margaret Chren, Roy Grekin, Maria L Wei
发表日期
2017/2/22
期刊
JAMA Dermatology
简介
Importance
Melanoma in situ (MIS) is increasing in incidence, and expert consensus opinion recommends surgical excision for therapeutic management. Currently, wide local excision (WLE) is the standard of care. However, Mohs micrographic surgery (MMS) is now used to treat a growing subset of individuals with MIS. During MMS, unlike WLE, the entire cutaneous surgical margin is evaluated intraoperatively for tumor cells.
Objective
To assess the outcomes of patients with MIS treated with MMS compared with those treated with WLE.
Design, Setting, and Participants
Retrospective review of a prospective database. The study cohort consisted of 662 patients with MIS treated with MMS or WLE per standard of care in dermatology and surgery (general surgery, otolaryngology, plastics, oculoplastics, surgical oncology) at an academic tertiary care referral center from January 1, 1978, to December 31, 2013, with follow …
学术搜索中的文章
A Nosrati, JG Berliner, S Goel, J McGuire, V Morhenn… - JAMA dermatology, 2017