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This paper deals with the development of a procedure aimed at defining a seismic risk mitigation strategy for public buildings in terms of prioritization, time required and funds. The procedure is based on a global risk index involving the entire building stock under study thus facilitating an examination of risk variation over time up to its final value. Relationships between the current seismic capacity–demand ratios and the required strengthening costs (cost models) have been developed. Each of the assumed cost models has a different target in terms of capacity–demand ratio to be obtained after strengthening, basically ranging between full retrofit and upgrading. The procedure has been applied to 69 hospital buildings located in Basilicata region for which the vulnerability data was available as a result of a large assessment program set up by the regional government. Priorities have been defined on the basis of …