作者
Anjali Jain, Konda Reddy Kunduru, Arijit Basu, Boaz Mizrahi, Abraham J Domb, Wahid Khan
发表日期
2016/12/15
来源
Advanced drug delivery reviews
卷号
107
页码范围
213-227
出版商
Elsevier
简介
Poly(lactic acid) and its copolymers have revolutionized the field of drug delivery due to their excellent biocompatibility and tunable physico-chemical properties. These copolymers have served the healthcare sector by contributing many products to combat various diseases and for biomedical applications. This article provides a comprehensive overview of clinically used products of poly(lactic acid) and its copolymers. Multi-dimension information covering product approval, formulation aspects and clinical status is described to provide a panoramic overview of each product. Moreover, leading patented technologies and various clinical trials on these products for different applications are included. This review focuses on marketed injectable formulations of PLA and its copolymers.
引用总数
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A Jain, KR Kunduru, A Basu, B Mizrahi, AJ Domb… - Advanced drug delivery reviews, 2016