作者
Jose B Cibelli, Kathleen A Grant, Karen B Chapman, Kerrianne Cunniff, Travis Worst, Heather L Green, Stephen J Walker, Philip H Gutin, Lucy Vilner, Viviane Tabar, Tanja Dominko, Jeff Kane, Peter J Wettstein, Robert P Lanza, Lorenz Studer, Kent E Vrana, Michael D West
发表日期
2002/2/1
期刊
Science
卷号
295
期号
5556
页码范围
819-819
出版商
American Association for the Advancement of Science
简介
Parthenogenesis is the process by which an egg can develop into an embryo in the absence of sperm. This process has been characterized to some extent in nonhuman primates (1, 2); however, to date, no primate parthenogenetic embryonic stem (ES) cell lines have been derived. Although attempts to obtain full-term mouse and bovine parthenogenetic individuals have failed (3–5), chimeras of parthenogenetic cells with biparentally derived embryonic tissues have generated apparently normal offspring
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JB Cibelli, KA Grant, KB Chapman, K Cunniff, T Worst… - Science, 2002