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Background. Malaria and helminth infections are major public health issues in sub‐Saharan Africa including Cameroon. This study was aimed at determining the prevalence and risk factors associated with malaria and helminth coinfection among children in the Douala Gyneco‐Obstetric and Pediatric Hospital (HGOPED) in Douala, southwestern Cameroon. Material and Methods. The study was a hospital‐based cross‐sectional study that took place from January to July 2020 where 203 children were involved. Blood samples were collected from the children and thick blood smears were prepared and examined microscopically for malaria parasites. Stool samples were also collected and examined through the Kato‐Katz technique for the identification of helminth eggs. Demographic and socioeconomic data and information of participant’s knowledge on the transmission of malaria and helminth infections were …