作者
Sharad Goyal, Ann W Silk, Sibo Tian, Janice Mehnert, Shabbar Danish, Sinthu Ranjan, Howard L Kaufman
发表日期
2015/8/1
来源
JAMA oncology
卷号
1
期号
5
页码范围
668-676
出版商
American Medical Association
简介
Importance
The treatment of multiple brain metastases (MBM) from melanoma is controversial and includes surgical resection, stereotactic radiosurgery (SRS), and whole-brain radiation therapy (WBRT). Several new classes of agents have revolutionized the treatment of metastatic melanoma, allowing some subsets of patients to have long-term survival. Given this, management of MBM from melanoma is continually evolving.
Objective
To review the current evidence regarding the treatment of MBM from melanoma.
Evidence Review
The PubMed database was searched using combinations of search terms and synonyms for melanoma, brain metastases, radiation, chemotherapy, immunotherapy, and targeted therapy published between January 1, 1995, and January 1, 2015. Articles were selected for inclusion on the basis of targeted keyword searches, manual review of bibliographies, and whether the article was a …
学术搜索中的文章
S Goyal, AW Silk, S Tian, J Mehnert, S Danish… - JAMA oncology, 2015