作者
Celia Cardozo, Guillermo Cuervo, Miguel Salavert, Paloma Merino, Francesca Gioia, Mario Fernández-Ruiz, Luis E López-Cortés, Laura Escolá-Vergé, Miguel Montejo, Patricia Muñoz, Manuela Aguilar-Guisado, Pedro Puerta-Alcalde, Mariona Tasias, Alba Ruiz-Gaitán, Fernando González, Mireia Puig-Asensio, Antonio Vena, Francesc Marco, Javier Pemán, Jesús Fortún, José María Aguado, Benito Almirante, Alejandro Soriano, Jordi Carratalá, Carolina Garcia-Vidal
发表日期
2020/3/1
期刊
Journal of Antimicrobial Chemotherapy
卷号
75
期号
3
页码范围
730-737
出版商
Oxford University Press
简介
Background
Candidaemia is a leading cause of bloodstream infections in hospitalized patients all over the world. It remains associated with high mortality.
Objectives
To assess the impact of implementing an evidence-based package of measures (bundle) on the quality of care and outcomes of candidaemia.
Methods
A systematic review of the literature was performed to identify measures related to better outcomes in candidaemia. Eight quality-of-care indicators (QCIs) were identified and a set of written recommendations (early treatment, echinocandins in septic shock, source control, follow-up blood culture, ophthalmoscopy, echocardiography, de-escalation, length of treatment) was prospectively implemented. The study was performed in 11 tertiary hospitals in Spain. A quasi-experimental design before and during bundle implementation (September …
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C Cardozo, G Cuervo, M Salavert, P Merino, F Gioia… - Journal of Antimicrobial Chemotherapy, 2020