作者
Meeri N Kim, Turgut Durduran, Suzanne Frangos, Brian L Edlow, Erin M Buckley, Heather E Moss, Chao Zhou, Guoqiang Yu, Regine Choe, Eileen Maloney-Wilensky, Ronald L Wolf, M Sean Grady, Joel H Greenberg, Joshua M Levine, Arjun G Yodh, John A Detre, W Andrew Kofke
发表日期
2010/4
期刊
Neurocritical care
卷号
12
页码范围
173-180
出版商
Humana Press Inc
简介
Background
This study assesses the utility of a hybrid optical instrument for noninvasive transcranial monitoring in the neurointensive care unit. The instrument is based on diffuse correlation spectroscopy (DCS) for measurement of cerebral blood flow (CBF), and near-infrared spectroscopy (NIRS) for measurement of oxy- and deoxy-hemoglobin concentration. DCS/NIRS measurements of CBF and oxygenation from frontal lobes are compared with concurrent xenon-enhanced computed tomography (XeCT) in patients during induced blood pressure changes and carbon dioxide arterial partial pressure variation.
Methods
Seven neurocritical care patients were included in the study. Relative CBF measured by DCS (rCBFDCS), and changes in oxy-hemoglobin (ΔHbO2), deoxy-hemoglobin (ΔHb), and total hemoglobin concentration (ΔTHC), measured by …
引用总数
学术搜索中的文章
MN Kim, T Durduran, S Frangos, BL Edlow… - Neurocritical care, 2010