作者
Roberto Gennari, Giuseppe Curigliano, Nicole Rotmensz, Chris Robertson, Marco Colleoni, Stefano Zurrida, Franco Nole, Filippo de Braud, Laura Orlando, Maria Cristina Leonardi, Viviana Galimberti, Mattia Intra, Paolo Veronesi, Giuseppe Renne, Saverio Cinieri, Riccardo A Audisio, Alberto Luini, Roberto Orecchia, Giuseppe Viale, Aron Goldhirsch
发表日期
2004/9/15
期刊
Cancer: Interdisciplinary International Journal of the American Cancer Society
卷号
101
期号
6
页码范围
1302-1310
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
BACKGROUND
Aging remains one of the single greatest risk factors for the development of new breast carcinoma. The aim of the study was to evaluate the relation between biologic features at first diagnosis of breast carcinoma and treatment choice for postmenopausal women ≥ 50 years to optimize treatment in the elderly.
METHODS
The sample included 2999 consecutive postmenopausal patients referred for surgery at the European Institute of Oncology (Milan, Italy) from April 1997 to February 2002. The patients were grouped according to age: young postmenopausal (YPM; 50–64 years, n = 2052), older postmenopausal (OPM; 65–74, n = 801), and elderly postmenopausal (EPM; ≥ 75, n = 146).
RESULTS
EPM patients referred to surgery had larger tumors compared with YPM patients (pT4: 6.7% vs. 2.4%) as well as greater lymph node involvement (lymph node positive: 62.5% vs. 51.3%). EPM patients …
引用总数
学术搜索中的文章
R Gennari, G Curigliano, N Rotmensz, C Robertson… - Cancer: Interdisciplinary International Journal of the …, 2004