作者
Marine Dekervel, Nicolas Henry, Massimo Torreggiani, Lise-Marie Pouteau, Jean-Paul Imiela, Chloé Mellaza, Anne-Sophie Garnier, Amaury Dujardin, Marine Asfar, Alexandra Ducancelle, Axelle Paquin, Sophie Blanchi, Virginie Besson, Giorgina Barbara Piccoli, Jean-François Augusto
发表日期
2021/11
期刊
Clinical Kidney Journal
卷号
14
期号
11
页码范围
2349-2355
出版商
Oxford University Press
简介
Background
Humoral response against sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after two doses of BNT162b2 (Pfizer-BioNTech) has been proven to be less intense in maintenance dialysis patients as compared with healthy subjects, leading the French authorities to recommend a third injection in this population. Here we investigated the response to the third injection in two cohorts of haemodialysis (HD) patients.
Methods
Data from two prospective observational cohorts were collected. In the first (‘systematic’) cohort, patients from two HD centres (n = 66) received a third injection of BNT162b2, regardless of the response after two injections. In the second (‘conditional’) cohort, the injection was only prescribed to patients (n = 34) with no or low response to the previous two doses. In both cohorts, the third dose was injected 1–2 months after the second …
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