作者
Marco Falcone, Giusy Tiseo, C Tascini, A Russo, Emanuela Sozio, Giammarco Raponi, CHIARA Rosin, Pasquale Pignatelli, P Carfagna, Alessio Farcomeni, ROBERTO Luzzati, Francesco Violi, Francesco Menichetti, Mario Venditti
发表日期
2017/6/1
期刊
European journal of internal medicine
卷号
41
页码范围
33-38
出版商
Elsevier
简介
Background
An increasing prevalence of candidemia has been reported in Internal Medicine wards (IMWs). The aim of our study was to identify risk factors for candidemia among non-neutropenic patients hospitalized in IMWs.
Methods
A multicenter case–control study was performed in three hospitals in Italy. Patients developing candidemia (cases) were compared to patients without candidemia (controls) matched by age, time of admission and duration of hospitalization. A logistic regression analysis identified risk factors for candidemia, and a new risk score was developed. Validation was performed on an external cohort of patients.
Results
Overall, 951 patients (317 cases of candidemia and 634 controls) were included in the derivation cohort, while 270 patients (90 patients with candidemia and 180 controls) constituted the validation cohort. Severe sepsis or septic shock, recent Clostridium difficile infection …
引用总数
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