作者
Matteo Bassetti, Daniele Roberto Giacobbe, Paolo Bruzzi, Emanuela Barisione, Stefano Centanni, Nadia Castaldo, Silvia Corcione, Francesco Giuseppe De Rosa, Fabiano Di Marco, Andrea Gori, Andrea Gramegna, Guido Granata, Angelo Gratarola, Alberto Enrico Maraolo, Malgorzata Mikulska, Andrea Lombardi, Federico Pea, Nicola Petrosillo, Dejan Radovanovic, Pierachille Santus, Alessio Signori, Emanuela Sozio, Elena Tagliabue, Carlo Tascini, Carlo Vancheri, Antonio Vena, Pierluigi Viale, Francesco Blasi
发表日期
2021/12
期刊
Infectious Diseases and Therapy
卷号
10
期号
4
页码范围
1837-1885
出版商
Springer Healthcare
简介
Introduction
The Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) constituted an expert panel for developing evidence-based guidance for the clinical management of adult patients with coronavirus disease 2019 (COVID-19) outside intensive care units.
Methods
Ten systematic literature searches were performed to answer ten different key questions. The retrieved evidence was graded according to the Grading of Recommendations Assessment, Development, and Evaluation methodology (GRADE).
Results and Conclusion
The literature searches mostly assessed the available evidence on the management of COVID-19 patients in terms of antiviral, anticoagulant, anti-inflammatory, immunomodulatory, and continuous positive airway pressure (CPAP)/non-invasive ventilation (NIV) treatment. Most evidence was deemed as of low certainty, and in some cases, recommendations …
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M Bassetti, DR Giacobbe, P Bruzzi, E Barisione… - Infectious Diseases and Therapy, 2021