作者
Melissa J Suter, Benjamin J Vakoc, Patrick S Yachimski, Milen Shishkov, Gregory Y Lauwers, Mari Mino-Kenudson, Brett E Bouma, Norman S Nishioka, Guillermo J Tearney
发表日期
2008/10/1
期刊
Gastrointestinal endoscopy
卷号
68
期号
4
页码范围
745-753
出版商
Mosby
简介
BACKGROUND
Optical coherence tomography (OCT) is a cross-sectional, high-resolution imaging modality that has been shown to accurately differentiate esophageal specialized intestinal metaplasia (SIM) from gastric cardia at the squamocolumnar junction (SCJ) and diagnose high-grade dysplasia and intramucosal carcinoma in patients with SIM. The clinical utility of OCT has been limited, however, by its inability to acquire images over large areas.
OBJECTIVE
The aim of this study was to use recently developed high-speed OCT technology, termed optical frequency domain imaging (OFDI), and a new balloon-centering catheter (2.5 cm diameter) to demonstrate the feasibility of large area, comprehensive optical microscopy of the entire distal esophagus (∼6.0 cm) in patients.
DESIGN
A pilot feasibility study.
SETTING
Massachusetts General Hospital.
PATIENTS
Twelve patients undergoing routine EGD …
引用总数
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