作者
Guillermo J Tearney, Sergio Waxman, Milen Shishkov, Benjamin J Vakoc, Melissa J Suter, Mark I Freilich, Adrien E Desjardins, Wang-Yul Oh, Lisa A Bartlett, Mireille Rosenberg, Brett E Bouma
发表日期
2008/11
期刊
JACC: Cardiovascular imaging
卷号
1
期号
6
页码范围
752-761
出版商
American College of Cardiology Foundation
简介
Objectives
We present the first clinical experience with intracoronary optical frequency domain imaging (OFDI) in human patients.
Background
Intracoronary optical coherence tomography (OCT) is a catheter-based optical imaging modality that is capable of providing microscopic (∼7-μm axial resolution, ∼30-μm transverse resolution), cross-sectional images of the coronary wall. Although the use of OCT has shown substantial promise for imaging coronary microstructure, blood attenuates the OCT signal, necessitating prolonged, proximal occlusion to screen long arterial segments. OFDI is a second-generation form of OCT that is capable of acquiring images at much higher frame rates. The increased speed of OFDI enables rapid, 3-dimensional imaging of long coronary segments after a brief, nonocclusive saline purge.
Methods
Volumetric OFDI images were obtained in 3 patients after intracoronary stent deployment …
引用总数
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GJ Tearney, S Waxman, M Shishkov, BJ Vakoc… - JACC: Cardiovascular imaging, 2008